Description
DNA contamination in final RNA preparations may interfere with several downstream applications such as gene expression analysis. Incubation with the RNase-free DNase I set ensures complete DNA removal from RNA solutions, as this enzyme hydrolyzes phosphodiester bonds of dsDNA, ssDNA, chromatin, and DNA-RNA hybrid molecules, without compromising RNA yield and integrity. This set can be used for both DNase digestion in solution as well as “in-column” digestion in combination with GRiSP’s GRS total RNA Purification Kits.