Description
Xpert DNA Purification Magnetic Beads consists of paramagnetic particles coated with carboxyl groups that reversibly bind DNA (Solid Phase Reversible Immobilization). The magnetic beads are supplied in a buffer that has been optimized in order to selectively and reversibly bind DNA fragments from 100bp up to 1kb and even much larger. This allows for easy PCR clean-up, as primers, primer-dimers, dNTPs, enzymes, excess salts, and other impurities can be removed quickly and efficiently by a simple washing procedure. Because this purification method does not require centrifugation or vacuum filtration, it can be readily adapted to 96-well or 384-well microplate automation platforms. Moreover, these beads can be seamlessly integrated into NGS Library preparation workflows.