Xpert Purification Magnetic Beads consists of paramagnetic particles coated with carboxyl groups that reversibly bind DNA (solid phase reversible immobilization) . The magnetic beads are supplied in a buffer that has been optimized in order to selectively bind DNA fragments of 100bp and larger. Primers, primer dimers, dNTPs, enzymes, excess salts, and other impurities can be removed quickly and efficiently by a simple washing procedure. Because this purification method does not require centrifugation or vacuum filtration, it can be readily adapted to 96-well or 384-well microplate automation platforms. Moreover, these beads can be seamlessly integrated into NGS Library preparation workflows.